Because Frankfort is bisected by the steep gorge of the Kentucky River, east–west transportation through the city was historically a challenge.

Immediately after crossing the river, the road reenters Frankfort and ascends toward Its eastern terminus at a single-point urban interchange with US 60 and US 421.

KY 676 begins at an intersection with US 127 in Frankfort, heading northeast on East–West Connector, a four-lane divided highway.

The road winds southeast before heading east again as it passes through more woodland with some residential neighborhoods, coming to a bridge over a R.J. Corman Railroad line.

KY 676 reaches its eastern terminus at a single-point urban interchange with US 60 and US 421, where the road continues east as part of US 421.