According to the Safavid official and chronicler, Fażli Ḵuzāni, Ketevan showed characteristic mercy to Constantine's surviving supporters and his Qizilbash officers.

After the uprising she negotiated with Shah Abbas I of Iran who was the suzerain over Georgia, to confirm her underage son, Teimuraz I, as king of Kakheti, while she assumed the function of a regent.

In 1614, sent by Teimuraz as a negotiator to Shah Abbas, Ketevan effectively surrendered herself as an honorary hostage in a failed attempt to prevent Kakheti from being attacked by the Iranian armies.

She was held in Shiraz for several years until Abbas I, in an act of revenge for the recalcitrance of Teimuraz, ordered the queen to renounce Christianity, and upon her refusal, had her tortured to death with red-hot pincers in 1624.

[citation needed] Portions of her relics were clandestinely taken by the St. Augustine Portuguese Catholic missioners, eyewitnesses of her martyrdom, to Georgia, where they were interred at the Alaverdi Monastery.

[5] The Georgian monk Grigol Dodorkeli-Vakhvakhishvili of the David Gareja Monastery was another near-contemporaneous author whose writings, a hagiographic work as well as several hymns, focus on Ketevan's life and martyrdom.

The Scottish poet William Forsyth composed the poem The Martyrdom of Kelavane (1861), based on Jean Chardin's account of Ketevan's death.

[6] In 2008, it was discovered that Graça Convent in Lisbon, Portugal contained a previously unknown, large panoramic azulejo depicting Queen Ketavan's martyrdom in Persia.

These historical sources stated that Ketevan's palm and arm bone fragments were kept inside a stone urn beneath a specific window within the Chapter Chapel of the Augustinian convent.