Kane was born in Philadelphia, Pennsylvania, graduated from Coastal Carolina University in 1998[3][4] and later the William Esper Studio in New York City.
[5] Kane made his screen debut appearing in a small part in the 2000 drama film, Swimming and later made guest appearances on Law & Order, One Life to Live and Law & Order: Special Victims Unit.
[6] With one of the members, Amy Schumer, Kane produced the Comedy Central sketch comedy series, Inside Amy Schumer from 2013 to 2022, receiving Primetime Emmy Award for Outstanding Scripted Variety Series in 2015.
[7] He also made 20-episodes recurring appearance on Inside Amy Schumer playing various roles and directed two episodes during the final season.
On television, he guest-starred on White Collar, Blue Bloods, No Activity and FBI: Most Wanted.