He played 2016 with the High-A Bradenton Marauders where he posted a .277 batting average with four home runs and 57 RBIs in 118 games.

[6][7] In 2017, Kramer played with the Double-A Altoona Curve, batting .297 with six home runs and 27 RBIs[8] in 53 games before a fractured right hand ended his season in June.

[9] Kramer began the 2018 season with the Triple-A Indianapolis Indians of the International League and was called up to the majors for the first time on September 4.

Kramer spent the majority of the 2019 season with Indianapolis, playing in only 22 games with the Pirates, with whom he batted .167/.260/.190 with 5 RBI.

[15] On June 1, 2022, Kramer affirmed that he had retired from professional baseball and has since started his own solar power firm after his release from the Brewers organization.