[2] It is located 3 nautical miles (5.6 km; 3.5 mi) southwest of Meridian, a city in Lauderdale County, Mississippi, United States.

[7] Meridian Regional Airport was established in 1928 and opened in November 1930 with the completion of the terminal, hangar, powerhouse, and a graded and packed dirt runway.

The brothers maintained their flying school at the new field as well as their other duties, such as selling commercial airline tickets, operating the terminal and hangar, and handling airmail delivery schedules.

The hangar and offices used by the Key brothers preceding and following the flight are still in use today and are listed in the National Register of Historic Places.

Delta flew nonstop from both Atlanta and Memphis flown with de Havilland Canada DHC-7 Dash 7 and Embraer EMB-110 Bandeirante turboprop aircraft.

[12] Southern Airways began serving Meridian in 1962 with direct flights to Atlanta, Memphis, and New Orleans, making intermediate stops en route at other cities.

Before merging with Air Midwest in 1985, Scheduled Skyways was operating four direct flights a day into Meridian from Memphis with Nord 262 and Fairchild Swearingen Metroliner commuter prop jets, with all of these flights making an intermediate en-route stop in Tupelo, Mississippi.

The carrier flew Fairchild Swearingen Metroliner and British Aerospace Jetstream 31 commuter prop jet aircraft.

Aircraft Rescue and Firefighting (ARFF) capabilities are provided by the Air National Guard due to Key Field's stationing of the 186 ARW.

In 2008, the 186 ARW entered into an arrangement with the active Air Force, hosting an operational training detachment for USAF-operated MC-12W aircraft under a program known as Project Liberty.

A derivative of the C-12 Huron, the MC-12W Liberty platform was created in response to Defense Secretary Robert Gates' initiative to better support war fighters on the ground with increased ISR in theatre.

The BRAC Report also states that the 186 ARW's aircraft rescue and firefighting (ARFF) positions are to be reassigned to the Mississippi Air National Guard's 172nd Airlift Wing (172 AW), an AMC-gained C-17 Globemaster III unit at Jackson International Airport.

These transfers are to take place in 2010 and 2011, although the recent addition of the MC-12W Project Liberty program at Key Field may delay or eliminate the ARFF reassignment.

[8] The old terminal building, hangar, and powerhouse at Key Field together form the earliest surviving airport complex in the state of Mississippi.

[22] After being listed under the National Register for Historic Places, the buildings were rehabilitated for use as a Cessna flight training school and repair shop.

The second floor, a single room that originally housed the weather bureau, has a central door that opens onto the porch roof, forming an observation deck overlooking the airfield.

There is a small office and washroom on the east end, and a staircase leads to a narrow second floor room that overlooks the workroom and hangar storage area.

[8] Located on the east side of the hangar, the Powerhouse is a one-story, one-by-one bay building with another gabled roof and parapet walls.

[8] For the 12-month period ending March 31, 2021, the airport had 86,751 aircraft operations: 71% military, 25% general aviation, 4% air taxi, and <1% scheduled commercial.