It is 249 miles 25 chains (401.2 km) from London Paddington via Box and Plymouth Millbay.

[2] The goods facilities were used for marshalling trains to and from the Cornwall Railway branch into the naval dockyard, opened on 20 June 1867, which enters the dockyard between the station and Weston Mill viaduct.

[4] The station was the most westard point which a GWR King class locomotive was permitted to operate.

Keyham is served by Tamar Valley Line services from Plymouth to Gunnislake,[5] and by a few trains on the Cornish Main Line to and from Penzance, some of which continue eastwards towards Exeter St Davids.

It is part of the Dartmoor Sunday Rover network of integrated bus and rail routes.