Keynan Anthony Middleton (born September 12, 1993) is an American professional baseball pitcher who is a free agent.

[2] He made his professional debut with the Arizona League Angels and was promoted to the Orem Owlz during the season.

He started 2016 with the Inland Empire 66ers and was promoted to the Arkansas Travelers and Salt Lake Bees during the season.

After striking out the first two batters he faced, Middleton yielded a solo home run to Baltimore catcher Caleb Joseph and then got outfielder Joey Rickard to pop out on the infield to end the game.

On May 14, Middleton was placed on the disabled list for the second time in the year due to suspected damage to the UCL in his right elbow.

[11] On August 28, Middleton cleared waivers and was assigned outright to the Triple-A Tacoma Rainiers.

He was assigned to the Triple-A Charlotte Knights to begin the year, and recorded three strikeouts in three scoreless innings pitched.

On February 3, 2024, Middleton signed a one-year contract with the St. Louis Cardinals that contained a club option for the 2025 season.