The Keystone Hotel is an historic, American home that is located in Hummelstown, Dauphin County, Pennsylvania.

It was added to the National Register of Historic Places in 1985.

It was originally a two-and-one-half-story, rectangular, brick building with gable roof that was designed in a vernacular, Federal style.

The 1850 expansion raised and flattened the original roofline, and added a three-bay, three-story brick addition to the east side.

[2] It was added to the National Register of Historic Places in 1985.