The Keystone Hotel is a historic hotel building in McCook, Nebraska.

It was built as a hotel in 1922, and it was remodelled as a retirement facility in 1970.

[2] It was designed in the Renaissance Revival style by Archer and Gloyd, an architectural firm based in Kansas City, Missouri.

[2] It has been listed on the National Register of Historic Places since July 5, 2001.

This article about a property in Nebraska on the National Register of Historic Places is a stub.