Khadija Mohamed Al-Makhzoumi (Somali: Khadija Mohamed Al-makhzoumi, Arabic: خديجة محمد المخزومي) is a Somali/ diplomat and politician who currently serves as the Minister of Family & Human Rights Development in Somalia and also a member of the Federal Parliament of Somalia's House of the People.

She assumed office as Minister of Environment and Climate change on August 9, 2022, and is responsible for developing and implementing environmental policies, strategies, laws, and regulations in the country.

During her tenure as the Somali Ambassador to Pakistan, Khadija played a significant role in strengthening bilateral relations between the two countries.

This agreement, inked in May 2018, aimed to enhance administrative processes and improve security measures in Somalia.

Khadija's efforts in facilitating this agreement showcased her diplomatic skills and commitment to promoting cooperation and development between nations.

Later on, from 2011 to 2013, Ambassador Khadija Mohamed Al-Makhzoumi was deployed as the Senior Political Adviser, Minister of Foreign Affairs, Somalia.