Produced on a budget of ₹50 crore, Principal photography began in June 2016 in Hyderabad.

However, he changes his mind after encountering Subbalakshmi, his childhood friend, who deceives him into thinking she reciprocates his feelings.

However, an MNC owned by Aggarwal tricked the villagers into giving up their land for a factory.

Shankar was arrested, and six villagers committed suicide to draw media attention and secure his release.

Unable to bring the villagers back in time, Seenu takes drastic measures to draw attention to their cause.

Seenu, Subbalakshmi, Malli, and the old-age home residents block Hyderabad's water supply by sitting on the pipelines.

On the eve of the verdict, Seenu's impersonation is exposed, but he assures the residents of his genuine commitment to their cause and promises to rescue Shankar from Aggarwal.

[13] The film features Chiranjeevi and Kajal Aggarwal was finalised as the heroine in late July 2016.

[15] Principal photography commenced on 23 June 2016[13][16] as key sequences being shot at Chanchalguda Central Jail in Hyderabad.

[17] Later, in August 2016 Chiranjeevi and Kajal joined the shooting at Rajiv Gandhi International Airport, Hyderabad.

"[27] 123 Telugu gave the film 3.25 writing "On the whole, Khaidi No 150 is a typical mass entertainer.

The film is set to take record openings and has everything that we expect from a star hero like Chiranjeevi.

He makes a thumping comeback and proves that even at this age he can give every star hero a run for their money.

"[28] The Indian Express gave the film 3.5 writing "DSP songs do pump up the narrative but a slight disappointment is that dancer Chiru of Indra and Tagore is quite not in shape for a new step.

"[30] Firstpost gave the film three out of five writing "Directed by VV Vinayak, Khaidi No 150's objective, in the end, isn't to really tell an emotional story.