Its current fully-roofed, 45,857-seat configuration was opened in 2017, following a previous reconfiguration in 2005 that incorporated the stadium into the Aspire Zone complex and added a roofed grandstand; boosting its capacity from 20,000 to 40,000.

Track and field events at the 2006 Asian Games, 2011 Pan Arab Games, and 2019 World Athletics Championships were held at the stadium, and World Athletics has since organised the annual Doha Diamond League event there as part of its Diamond League series.

Over the eastern side, a large arch with additional light fixtures were added, which was used as a platform; this was used during the games' opening ceremony to launch fireworks from.

[6] The stadium's reconfiguration in 2005 was part of the larger Doha Sports City urban renewal project in Al Rayyan, later known as the Aspire Zone complex.

[8] After the rights to host the 2022 FIFA World Cup were awarded to Qatar in December 2010, Khalifa International Stadium was reconfigured again to stage matches during the tournament.

[10][11] Upon its reopening in 2017, it became the first stadium to receive a four-star rating from the FIFA-endorsed Global Sustainability Assessment System of the Middle East and North Africa,[12] and was the first of the eight venues of the FIFA World Cup to open.

[20] The Supreme Committee for Delivery & Legacy (SC) and the Aspire Zone Foundation collaborated to renovate the stadium, which got underway in 2014.