Khanzada Begum (Persian: خانزاده بیگم; c. 1478 – 1545) was a Timurid princess and the eldest daughter of Umar Shaikh Mirza II, the amir of Ferghana.

She is also frequently mentioned in the Humayun-nama by her niece Gulbadan Begum, who calls her aunt 'Dearest Lady' (aka janam).

[1] Khanzada Begum was born c. 1478 in Andizhan, Ferghana, as the eldest daughter of Umar Sheikh Mirza and his first wife and chief consort Qutlugh Nigar Khanum, a princess of Moghulistan.

"[4] In July 1500, Khanzada's maternal aunt, Mihr Nigar Khanum, had been captured by Shaybani Khan and forcibly married to him, 'as part of the spoils'.

[7] In 1511, at the age of thirty-three, Khanzada was returned to Babur at Kunduz by Shah Ismail I (who had defeated Shaybani in the Battle of Marv), with an escort of soldiers.

Mahdi Khwaja presented his brother-in-law, Hindal, with a large amount of dowry and Khanzada Begum also gave extravagant gifts.

[12] Khanzada Begum died at Qabal-chak in September 1545 while she was accompanying her nephew, Humayun, who was on his way from Qandahar to meet his younger half-brother, Kamran Mirza.

[13] Khanzada Begum was portrayed by Drashti Dhami in the Hotstar Web series The Empire released on 27 August 2021[21]