Khao Noi–Khao Pradu Non-hunting Area is located about 25 km (16 mi) northeast of Phitsanulok city in Don Thong Subdistrict, Mueang Phitsanulok District and Ban Klang, Chai Nam, Wang Nok Aen Subdistricts, Wang Thong District and Ban Yang, Hin Lat, Khan Chong Subdistricts, Wat Bot District of Phitsanulok Province.

[3] The non-hunting area is 40 km (25 mi) long and has a maximum width of 5 km (3.1 mi),[4] total area is 129 km2 (50 sq mi) and is neighbouring by Song Khwae Non-hunting Area to the north, Khwae Noi National Park to the east and Thung Salaeng Luang National Park to the southeast.

The total mountained area is 88%, divided into 33% high slope mountain area (upper-slopes, shallow valleys, mountain tops and deeply incised streams) and 55% hill slope area (open slopes, u-shaped valleys and midslope ridges).

[7] In 1992 a survey was set up by the Phitsanulok Regional Forestry Office for Khao Noi–Khao Pradu forest area and many wild animals were found here.

In 1994 the forest area on both sides of the Khwae Noi River were surveyed and also many kinds of wild animals were found there.