Khao Phanom (Thai: เขาพนม, pronounced [kʰǎw pʰā.nōm]) is a district (amphoe) in Krabi province, Thailand.

The minor district (king amphoe) was created on 1 December 1967 by combining tambons Khao Phanom, Khao Din, and two villages of Khok Yang of Mueang Krabi district and tambon Sin Pun from Khlong Thom district.

[2] Neighboring districts are (from the north clockwise): Chai Buri and Phrasaeng of Surat Thani province; Thung Yai of Nakhon Si Thammarat province; and Lam Thap, Khlong Thom, Nuea Khlong, Mueang Krabi, Ao Luek, and Plai Phraya of Krabi Province.

The Khao Phanom Bencha National Park protects the forests around Phanom Bencha mountain, which at 1,397 m is the highest elevation in Krabi Province.

The district is divided into six subdistricts (tambons), which are further subdivided into 54 villages (mubans).