Khem Karan is a town and a nagar panchayat in Tarn Taran district of Patti tehsil of the Majha region of the Indian state of Punjab.

Many of the town's residents migrated from nearby villages between 1947 and 1965, such as Nathuwala, Qadiwind, Rohiwal, and Sehjra.

On 8 September, the Pakistani 1st Armoured Division and 11 Infantry Division under the command of Maj Gen Nasir Khan pushed an offensive towards Khem Karan, with the intent to capture Amritsar (a major city in Punjab, India) and the bridge on River Beas to Jalandhar.

After India breached the Madhupur canal on 11 September, the Khem Karan counter-offensive was halted, affecting Pakistan's strategy substantially.

The table below shows the population of different religious groups in Khem Karan town and their gender ratio, as of 2011 census.