Khok Samrong (Thai: โคกสำโรง, pronounced [kʰôːk sǎm.rōːŋ]) is a district (amphoe) of Lopburi province in central Thailand.

Kasetsart University's Lopburi campus is in Tambon Phaniat, Khok Samrong District.

Originally named Phu Kha, the minor district (king amphoe) was renamed Sa Bot in 1909.

Neighbouring districts are (from the north clockwise) Nong Muang, Sa Bot, Chai Badan, Phatthana Nikhom, Mueang Lopburi and Ban Mi.

Missing numbers are tambon which now form Nong Muang and Khok Charoen Districts.