Speer and Johnson met in 2004 when they played for Pastor Rudy Rasmus' St. John's Methodist Church gospel band in Houston, Texas.

[6] The two musicians attended a bar after Tuesday night rehearsal, and Speer revealed his extensive knowledge of music from around the globe.

[7] In 2007, Speer met Ochoa through friends, where they initially connected over a shared love of Afghan music and Middle Eastern architecture.

Before you even start, you have to know what you’re experimenting with first.”[17]A notable part of the band's visual style is the black wigs that Ochoa and Speer wear on stage and during promotional interviews and photoshoots.

[18] After touring with Bonobo, Khruangbin's song "Calf Born in Winter" was included on his 2013 Late Night Tales compilation.

[19] The song became one of the most popular tracks on the record, helping create an initial audience[12] for the band's first EP, History of Flight, and debut album, The Universe Smiles Upon You, in 2015.

Shortly thereafter, Khruangbin were named The Guardian's "New Band of the Week,"[16] opening for acts like Father John Misty,[8] Tycho,[21] Chicano Batman, and Massive Attack.

"[20] The band said the title of the record is also a reference to the diverse range of musical influences that inspired it, primarily from the Middle East.

[8] Later in the year they recorded live for Spotify an arrangement of the Indian song "Khuda Bhi Aasman Se", played by Mohammed Rafi in the movie Dharti.

[31][32][33] The band also relaunched their AirKhruang DJ series, and the following year appeared on Austin City Limits performing with Leon Bridges.

In January 2024, the band announced their fourth solo album, A La Sala, which was released on April 5, 2024, and shared a video for a new song, "A Love International.

[46] The most commonly used term to describe Khruangbin's music is Thai funk,[46] though the band members themselves challenge the convention of genres, publicly refusing to be pigeonholed into one particular label.

"[49] The New York Times wrote that Khruangbin's sound was so distinct and popular that "there now exists an entire subgenre of music broadly known as 'Khruangbin vibes.