In 2014, Khurram became the oldest player to score an ODI hundred as his unbeaten 132 helped his team to a six-wicket victory over Afghanistan in Dubai.
Khurram got one wicket in his first match, with the last ball of a ten-over spell, and took four for 32 in ten overs against Sri Lanka, including the top scorer of the innings Avishka Gunawardene who lofted a catch to the deep for 73.
Khurram was captain at the 2005 ICC Trophy, leading his team to a fifth place play-off where the winner would qualify for the 2007 World Cup.
Three months later, Khurram had to declare himself unavailable for the semi-final of the 2005 Intercontinental Cup, with Arshad Ali captaining the side in his place.
In June 2015, following the UAE's defeat to Ireland in the 2015–17 ICC Intercontinental Cup, Khurram announced his retirement from international cricket.