It is the northern terminus of Athens Metro Line 1, located 25.655 km from the starting point in Piraeus.

The station was opened on 10 August 1957, and was renovated for the 2004 Summer Olympics.

[1] Kifissia metro station was opened by the Hellenic Electric Railways on 10 August 1957, as part of the most recent extension of the line from Irakleio: the station was then renovated for the 2004 Summer Olympics, with the renovation works being completed on 14 July 2004.

On 3 March 2009, masked vandals destroyed a train waiting on one of station's platforms with Molotov cocktails, causing the service to be cut back to Eirini.

[2] On 7 July 2020, an Kifisias-bound terminating train[3] hit the buffers as it failed to slow while entering the station, with reports of no deaths and a total of 8 and 10 lightly injured in the incident.