In 2012, she teamed up with the director of Behind the Smile, Tunde Olaoye, to star in her debut feature film Married but living single where she worked with Funke Akindele, Joseph Benjamin, Femi Brainard and Joke Silva.

[5] Omeili has had roles in a number of TV series including The Valley Between,[6] NESREA Watch, Lekki Wives and Gidi Culture.

[8] Early 2016, she starred in the Nigerian Box Office hit Couple of Days, where her portrayal of the character Joke, got wonderful reviews from critics.

The film features Omeili, as the lead character, and Eric Didie, Bimbo Ademoye, Blessing Ambrose and Nathan Kingsley in supporting roles.

[12] In June 2018, Omeili began production of her debut full-length feature film, Run, which was directed by Uche Chukwu.

[13] The movie Run was released in cinemas on August 23, 2019 starring comedian Owen Gee, Rotimi Salami, Kelechi Udegbe, and Greg Ojefua.

[25] In 2018, Omeili won the best supporting actress award at the World Music & Independent Film Festival, which held in the Caribbean Islands for her role in the movie 3Some.