Wolfkill grew up in Pennsylvania and studied journalism and art at the University of Washington, road racing competitively on the side.

[6] Wolfkill recalled her parents giving them a great amount of latitude to be creative growing up, and that they were raised without regards to traditional gender roles.

For Midtown Madness, Wolfkill drove cars rigged with microphones around a racing track to gain authentic audio.

With later racing games, the art teams used computer-aided design data to build the cars and dynamometers to test the machines.

Wolfkill transitioned from PC-exclusive games to console titles, such as Project Gotham Racing, Fable, and Mass Effect.

Wolfkill and Ross spoke out against sexist comments in the game, threatening permanent bans from the Xbox Live service for offenders.

[11] Wolfkill executive produced Halo: The Master Chief Collection in 2014, before transitioning to overseeing the company's broader transmedia efforts.

[12] Wolfkill left 343 Industries in 2023 amid reorganization of the studio, becoming head of intellectual property expansion and entertainment for Microsoft.