Production was handled by Seven, Wyshmaster, David Sanders II, Robert Rebeck, Young Fyre, Jonah "Matic Lee" Appleby, Krizz Kaliko, Aaron Abeyta, Aaron Bradley, Antonio "Elmo" Wesley, Makzilla, Soleternity, UnderRated, and Tech N9ne himself, with Travis O'Guin serving as executive producer.

It features guest appearances from Krizz Kaliko, Kutt Calhoun, Big Scoob, BG Bulletwound, Bosko, Brother J, (həd) p.e., Ice Cube, Kottonmouth Kings, Lebowski, Liquid Assassin, Liz Suwandi, Mistah F.A.B., Paul Wall, Robert Rebeck, Scarface, Shawnna, Skatterman & Snug Brim, The Popper, The Weapon, and Strange Lane Choir.

)[2] Guests who were featured on the album include Paul Wall, Scarface, Shawnna, Brother J of X-Clan, Mistah F.A.B., Kottonmouth Kings, Hed PE, Krizz Kaliko, Kutt Calhoun, Skatterman & Snug Brim, BG Bulletwound, Liquid Assassin of Grave Plott, and Ice Cube.

[1] It was later revealed that Brotha Lynch Hung was supposed to be on Psycho Bitch II, but he would have been unable to get his verse back to Tech in time, thus he did not appear.

The video was directed by Estevan Oriol and featured several cameos such as the songs producer Young Fyre, fellow label mates Krizz Kaliko and Kutt Calhoun, actor Danny Trejo, as well as artists Boo-Yaa T.R.I.B.E., C-Bo, Glasses Malone, Krondon, and Skinhead Rob.