He started his career with Rosario Central, which he would represent in three different spells, moving to Spain in 1996 where he appeared for Zaragoza and Valencia, amassing La Liga totals of 182 matches and 23 goals during seven seasons and winning the national championship with the latter.

He appeared in his first game in La Liga on 8 September, playing 19 minutes in a 2–1 win against Sevilla[2] and, during his three-year spell in Aragon, shared teams with countryman Gustavo López who was also a winger.

Following the emergence of younger Vicente, he became surplus to requirements – only 13 appearances and 546 minutes of action in his last year, which also included a run-in with manager Rafael Benítez[5]– and left the Che as a free agent; additionally, he amassed UEFA Champions League combined totals of 31 matches and five goals, as they reached the final in 2000 and 2001, and was granted Spanish nationality in early January 2001.

On 4 August 2009, he joined San Lorenzo who was managed by former national teammate Diego Simeone; after the former's relegation, however, he decided to rejoin for a third spell and help in the Primera B Nacional campaign,[9] following which he retired at 37.

[14] He was selected by manager Marcelo Bielsa for his 1999 Copa América squad, scoring one of his nine goals in the nation's 2–0 group stage win against Uruguay as the former went on to reach the quarter-finals only to be eliminated by eventual champions Brazil.