[2] Smith was selected in the fourth round, 37th overall, by the Hamilton Tiger-Cats in the 2022 CFL Draft and signed with the team on May 9, 2022.

[2][4] On September 17, 2022, Smith scored his first touchdown on a 54-yard pass from Dane Evans in a victory against the Winnipeg Blue Bombers.

[2][5] He played in all 18 regular season games, starting in eight, where he had 17 catches for 247 yards and one touchdown and one two-point convert.

[6] In 2023, Smith had a more expanded role on offense as he played in 18 regular season games, starting in 15, where he had 56 receptions for 701 yards.

[6] He also had his first 100-yard receiving game and set single-game career highs on September 23, 2023, when he recorded nine catches for 156 yards in the team's loss to the Argonauts.