He was ranked among the top-300 offensive lineman in the class of 2020 and led the team with 25 wins for over three seasons.

[2] He was rated a two-star recruit and committed to play college football at Yale over offers from Central Michigan, Indiana State and Southern Illinois.

During the 2022 season, he started all 10 games at left tackle and was named first-team All-Ivy League.

[5][6] During the 2023 season, he played only four games due to a season-ending injury that required him having surgery.

[8] Amegadjie was selected in the third round with the 75th overall pick by the Chicago Bears in the 2024 NFL draft.