Kirby Muxloe is a large village and civil parish that forms part of the Blaby district of Leicestershire, England.

At the time the land in Kirby Muxloe was owned by Hugh de Grandesmaynel and by William Peverel.

His father, Sir Leonard Hastings, had owned a modest estate in Leicestershire and Gloucestershire, where the family had long been established.

On 14 April 1474 Hastings acquired the manorial right to Kirby from the Pakeman family, although he had rented it for some years previous to this.

An early Quaker, John Penford, was a substantial resident of Kirby Muxloe and member of the Leicester Quarterly Meeting.

A business meeting of the Society held at his home to consult on works of charity in 1670 was interrupted by informers, with the result that Penford and others were heavily fined.

A German bomber returning from an attack on Coventry emptied its load on two streets, destroying the Free Church and several houses.