The game was released in Japan on Windows and OS X on November 25, 2016, bundled with the third Blu-ray box set of anime series Danganronpa 3: The End of Hope's Peak High School.

In the non-canon Extraterrestrials vs. Earth Plants Against Invaders Defense Force chapter, he takes on a more prominent role in the fight against the Rhinogradentia, developing a romantic relationship with Kyoka; in the shared dreamscape-set Extra Scenario chapter, he briefly appears as the owner of the mansion, providing Matsudaira CPR while he dreams of kissing Kyoko, briefly awakening him from his coma.

In the shared dreamscape-set Extra Scenario chapter, Matsudaira sees a single Rhinogradentia alongside Hiro Hagakure while passing by a fireplace.

Kirigiri Sou has three main narratives based on the decisions of the player character; the canon narrative chapter, The Plant Girl, depicts normal freshman Kouhei Matsudaira assisting Ultimate Detective Kyoko Kirigiri after she is contacted to investigate her apparent doppelgänger at a mysterious mansion.

Kirigiri Sou was announced and shown in the October 2016 issue of Famitsu by Spike Chunsoft, as a "sound" visual novel for personal computer systems Windows and OS X.