Kirtlebridge railway station was a station which served the rural area around Kirtlebridge and Eaglesfield, north of Annan in Dumfriesshire, Scotland; the location is now within the area of Dumfries and Galloway unitary council.

The station was served by local trains on the Caledonian Railway main line between Carlisle and Glasgow, now the West Coast Main Line, and the station was the junction for the Solway Junction Railway.

The station had a number of sidings, a goods shed, turntable, signal box, a bay platform and an interchange with the main line.

[2] A narrow gauge mineral line ran over the main line to serve local quarries and the old bridge survives as part of a narrow access lane.

Trains pass at speed on the electrified West Coast Main Line.