The name Kitisuru comes from a nearby river "Gĩtathuru" which was borrowed from the original inhabitants of the area who were mainly of the Kikuyu ethnic group.

Kitisuru is located approximately 9.5 kilometres (5.9 mi), by road, northwest of the central business district of Nairobi.

These include New Kitisuru, which borders Mwimuto in Kiambu County.

Educational institutions located in this area include the International School of Kenya (which caters mostly to US Embassy staff) and the School of the Nations (Kenya), a Christian-based international school established by South Korean missionaries..

Loresho, Kyuna and Lower Kabete Sub–locations form part of the greater Kitisuru Ward.