Klaas George de Vries (born 28 April 1943) is a retired Dutch politician of the Labour Party (PvdA) and jurist.

After the 1998 general election De Vries was appointed as Minister of Social Affairs and Employment in the Kok II cabinet, taking office on 3 August 1998.

De Vries was appointed as Minister of the Interior and Kingdom Relations following the resignation of Bram Peper, taking office on 24 March 2000.

De Vries also became active in the public sector and occupied numerous seats as a nonprofit director on several boards of directors and supervisory boards (Humanist Association, Parliamentary Documentation Center, Transnational Institute, International Fellowship of Reconciliation, Atlantic Association, Institute for Multiparty Democracy, ProDemos and the International Institute of Social History) and served on several state commissions and councils on behalf of the government (Council for Public Administration, Cadastre Agency, Advisory Council for Spatial Planning and Public Pension Funds APB) and as an advocate, lobbyist and activist for the Anti-war movement, Humanitarianism and Democracy.

In November 2014 De Vries announced his retirement from national politics and that he would not stand for the 2015 Senate election and continued to serve until the end of the parliamentary term on 9 June 2015.