[7] She is an artist under ABS-CBN's training and management subsidiary, Star Magic and was also a member of the Filipino singing quartet, Birit Queens.
[9] In 2001 when she was nine, she landed second place in Batang Kampeon where Almira Cercado of 4th Impact and Jake Zyrus (formerly Charice Pempengco) were also contestants.
De Guzman also competed in Star for a Night along with Angeline Quinto and Sarah Geronimo, the latter becoming her coach in the first season of The Voice of the Philippines.
[10] While an AB Music Production student at the De La Salle–College of Saint Benilde, she was member of a band called Turning Point.
[11] De Guzman auditioned on the first season of The Voice of the Philippines in 2013 with the song Tulak Ng Bibig by Julianne Tarroja.
All of the show's coaches, Bamboo Mañalac, Sarah Geronimo, Lea Salonga, and apl.de.ap (in order) turned their respective chair to express interest in mentoring her.
De Guzman shared after performing her audition song that she once joined Star for a Night which made Geronimo surprised as she did not recognize her at first.
[10] It was held at Teatrino, Promenade Mall on August 29, 2014, with Nyoy Volante, Juan Karlos Labajo, and Paolo Onesa as guests.
In May 2016, she joined Liezel Garcia and Emmanuelle Vera to form the group O Diva as part of ABS-CBN's music competition, We Love OPM, under the mentorship of KZ Tandingan.
The trio performed Ikaw Ang Pangarap, Katawan, Gaya ng Dati, Kung Kailangan Mo Ako (together with Power Chords group), Basang-basa Sa Ulan, Karakaraka, and Batang-Bata Ka Pa.
The group consistently ranked at the upper percentile each week and was exempted to compete during the semi-finals after gathering the most number of points across episodes.
[21] In May 2016, a vocal showdown was conducted in ASAP where De Guzman performed with Angeline Quinto, Morissette, and Jona who has just transferred to ABS-CBN from GMA Network.
In 2018, she and Michael Pangilinan covered "Araw-Araw, Gabi-Gabi" to serve as the theme song of the drama television series Araw Gabi.
She also had multiple visits on Umagang Kay Ganda, Kris TV, and Magandang Buhay where she was invited to be interviewed and to perform.