[2] Klein ISD is part of the taxation base for the Lone Star College System.

[11] It is board policy that all high schools include the name 'Klein' in honor of the district's namesake.

Some areas within the Spring and Tomball postal designations, and a portion of "Acres Homes" within the city limits of Houston are also served by Klein ISD.

For the 2018–2019 school year, Klein ISD received an overall score of 89, resulting in a B grade.

[23][24][25][26][27] School districts did not receive a rating for the 2011–2012 school year as the agency transitioned from using the Texas Assessment of Knowledge and Skills (TAKS) to the State of Texas Assessments of Academic Readiness (STAAR) as the basis for their accountability ratings.

[33] In the 2020–2021 school year, the district had a total of 52,824 students, starting from early childhood/pre-kindergarten education through grade 12.

The district had 3,617.09 teachers and 3,274.48 additional staff for a total of 6,891.57 employees on a full-time equivalent basis.

[36] Klein ISD, with voter approval, has sold bonds in 2004, 2008, and 2015 to provide funding for large infrastructure projects.

Other bond projects were classroom additions, security upgrades, technology infrastructure, and facility renovations.

[42] The district completed construction of Klein Cain High School in 2017 and Hofius Intermediate in 2018.

[43] Some classroom additions and renovations were removed from the 2015 bond project and the funds were used to repair facilities damaged by flooding.

Dual credit courses offered in the district include English 3, English 4, U.S. History, U.S. Government, Art History, Independent Study/Math, Pre-Calculus, Biology, Anatomy & Physiology, Correctional Services, and Court Systems & Practices.

[45] Klein ISD also offers many Advanced Placement (AP) classes at all five of their high schools in math, science, English, social studies, fine arts, and foreign language courses.

[46] The district offers the International Baccalaureate Diploma Program (IB) for 11th and 12th grade students at Klein Oak High School.

[51] Klein ISD operates the STEAM (the Science, Technology, Engineering, Arts with Math) Express, a bus that travels around the district with a drop down stage, teaching students about STEAM careers through a variety of activities.

The program is offered to all Klein ISD high school students who are admitted based on an application and interview process.