The Kleiweg originally served as the main connection between Rotterdam and Overschie where it crossed old creek bridges over the Rivers Schie and Rotte.

[4] Over time the road became increasingly lined by farms, houses and businesses—especially with major residential development occurring in the Kleiwegkwartier during the 1930s.

[6][7] Light industry, warehouses and tram depots are located in the southern part of the neighbourhood.

Its most western section, near the Overschiese Kleiweg, still retains characteristics of the area's rural origins.

[8] The neighbourhood benefits from good communication links with Rotterdam International airport, two railways stations, a tram and bus line and the A20 Autoroute all lying in close proximity.