Knyagininsky District (Russian: Княги́нинский райо́н) is an administrative district (raion), one of the forty in Nizhny Novgorod Oblast, Russia.

[3] It is located in the east of the oblast.

The area of the district is 769.9 square kilometers (297.3 sq mi).

[1] Its administrative center is the town of Knyaginino.

[6] The population of Knyaginino accounts for 56.3% of the district's total population.