Koharik Şirinian was born in Kumkapı quarter of Istanbul, Ottoman Empire, in 1860.
[2] In 1879, Şirinyan appeared with Bayzur Fasulyeciyan and Tahuki Hiranuş Satenik on stage in Bursa, in the beginning in a garden theatre called "Melekzade".. As theatre was sanctioned in Istanbul by Ottoman sultan Abdul Hamid II (reigned 1876–1909), Governor of Bursa Ahmed Vefik Pasha promoted it.
[2] Şirinyan was one of the most important members of the Ottoman-Armenian Serovpe Bengliyan Operetta Group thanks to her superior ability.
Şirinyan performed in the operatta roles of the Fiorella in Jacques Offenbach's Les brigands, Charles Lecocq's Giroflé-Girofla and Fatma in Tigran Chukhajian's Leblebici hor-hor agha as well as the male role of Prince Miniapur in Mongol te Great.
Şirinyan played in dramatic roles in Jacques Laurent's Frou-Frou and Georges Ohnet's Le Maître de forges.