The film explores the lives of Daniella Carter, Dominique Silver, Koko Da Doll, and Liyah Mitchell in New York and Georgia through interviews and re-enactments with actors.

The website's consensus reads: "Kokomo City is a rousing docu effort that illuminates trans lives within a world of adverse circumstance and invariable optimism.

[23] Peter Debruge of Variety wrote, "This doc rocks, using music to set the tempo for its snappy mix of head-turning talking heads, tongue-in-cheek reenactments and outside-the-box supporting visuals.

"[24] Lovia Gyarkye of The Hollywood Reporter wrote, "these women share their experiences with familial rejection, masculine sexual anxiety and a retaliatory world threatened by the dissolution of the gender binary.

"[25] In a review for the Los Angeles Times, Michael Rechtshaffen writes, "At once bracingly candid and buoyantly energetic, the first feature by Grammy-winning trans singer-songwriter D. Smith clearly earns the trust of its personable quartet, who require little prodding to share their experiences and philosophies as they navigate decidedly nontraditional paths.

"[6] Wendy Ide wrote for a review in The Observer, "For all the exaggerated winks in the music choices and provocative shots of beautifully lit buttocks, the film is an open and celebratory space in which the women can tell their stories.

"[4] Writing for Collider, Lisa Laman observed that 'Kokomo City' flourished as a work of subverting cinema norms by eschewing traditional documentary standards of othering marginalized voices on-screen, noting 'This is a movie where the personal stories of Mitchell, Carter, Silver, and Doll guide the feature along above all else.