The river originates on the Sikasso Plateau of Burkina Faso,[1] flows through the Cascades de Karfiguéla, forms a short section of the border between Burkina Faso and Ivory Coast before entering Ivory Coast.

[2] The banks of the Komoé are shaded by riparian forests along most of its length, providing an important habitat for wildlife and a source of agricultural water.

[2] A portion of the river in northern Ivory Coast is the source of the vegetative richness that earned that area a UNESCO World Heritage Site designation, Comoé National Park.

[3] At 09°42′11″N 004°35′10″W / 9.70306°N 4.58611°W / 9.70306; -4.58611 it is joined from the right (west) by the Léraba River, whereafter it flows southeast and forms the border between Burkina Faso and Ivory Coast for some 60 kilometres (37 mi), before it enters Ivory Coast four kilometres southwest of the village of Balanfodougou.

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