It was founded in 1967 by Dorothee and Konrad Fischer in Düsseldorf, in a disused alley in the center of the city.

[1][2] The gallery's first exhibition presented the work of Carl Andre to European audiences.

[4][5][6] The gallery has exhibited contemporary artists including Bernd and Hilla Becher, Wolfgang Laib, Jim Lambie, Sol LeWitt, Bruce Nauman, Manfred Pernice, Thomas Schütte, Gregor Schneider, Robert Smithson, and Paloma Varga Weisz.

[7] Artists who had their first solo exhibitions with him included Richard Long, Hanne Darboven, Lawrence Weiner and On Kawara.

[8] During the 1970’s, the gallery expanded its operations, with spaces in Zurich and Rome (with the Italian art dealer Gian Enzo Sperone).