Kotri–Attock Railway Line (Urdu: کوٹری–اٹک مرکزی ریل راستہ) (also referred to Main Line 2 or ML-2) is one of five main railway lines in Pakistan, operated and maintained by Pakistan Railways.

The total length of this railway line is 1,427 kilometers (887 mi).

The present day line consists of the following historic lines: The Mari–Attock Railway opened in 1891 as a 1,676 mm (5 ft 6 in) broad gauge railway line between Mari Indus and Attock.

[6] In 1956, Pakistan Western Railway converted the all 3 sections from 762 mm (2 ft 6 in) narrow gauge to 1,676 mm (5 ft 6 in) broad gauge.

Between 1969 and 1973, Pakistan Western Railways completed the gap section between Kashmore–Mari Indus and the line was also extended from Larkana to Kotri, thus linking Kotri to Attock.