When the area later forming the territory of the Kreis Meseritz was first annexed to Prussia from 1793 to 1807 it formed the Meseritzer Kreis (Meseritz district) within the Province of South Prussia, then governed by the Departement der Kriegs- und Domänen-Kammer zu Posen (Department of the chamber of war and domains at Posen).

After being part of the Duchy of Warsaw, the area returned to Prussia as a result of the Congress of Vienna.

After World War I, the administration had to be reorganized because the Region of Posen was split.

In 1920, the remaining district, measuring 706.49 square kilometres (272.78 sq mi), joined the newly founded Regierungsbezirk Schneidemühl, which became part of the Province of the Frontier March of Posen-West Prussia, established in 1922.

[2] In 1905, these civil registry offices (German: Standesamt) served the following towns in Kreis Meseritz: