He then played for five seasons with the University of Alberta Golden Bears from 1999 to 2003, during which time he registered 117 points (38 goals and 79 assists) in 102 games.
[3] Knoblauch continued his success with the Ice the following season, as the team posted a 36–26–5 record, but was swept by the Edmonton Oil Kings in the first round of the WHL playoffs.
[6] Knoblauch became the head coach of the Erie Otters of the Ontario Hockey League (OHL), a position he held from 2012 to 2017.
[3] During his seven total seasons as head coach of the Kootenay Ice and Erie Otters, Knoblauch compiled a record of 298–130–16–13,[1][2] and coached such players as Connor McDavid, Alex DeBrincat, André Burakovsky,[1][3] Connor Brown, Erik Černák, Anthony Cirelli, Travis Dermott, Sam Reinhart and Dylan Strome.
[2] On March 17, 2021, Knoblauch served as the New York Rangers' head coach when David Quinn and his staff were placed on the COVID-19 protocol list.
In Knoblauch's first game as head coach, the Rangers beat the Philadelphia Flyers 9–0 at Madison Square Garden.
On November 12, 2023, the Edmonton Oilers announced that they had hired Knoblauch as their head coach to replace the recently fired Jay Woodcroft.