Kneen has been shortlisted four times for the Queensland Premier's Literary Award.
As of 2009[update], Kneen was marketing and promotions officer at Avid Reader bookshop.
Affection (2009) deals with their childhood and young adulthood through the lens of sexuality, The Three Burials of Lotty Kneen (2021) is principally about their grandmother, and Fat Girl Dancing (2023) concerns their relationship with their body.
[5] Kneen's work has been described as "transgressive, sardonic, lyrical, comic; irresistibly erotic yet also romantic" and "acclaimed for its fearless honesty".
[14] Affection: A Memoir of Love, Sex & Intimacy, Text Publishing, 2009, ISBN 9781921656729[17] The Three Burials of Lotty Kneen: Travels with My Grandmother's Ashes, Text Publishing, 2021, ISBN 9781922330161[18] Fat Girl Dancing, Text Publishing, 2023, ISBN 9781922790217[19]