Kristi Kaye DuBose (born October 1, 1964) is a United States district judge of the United States District Court for the Southern District of Alabama.

Born in Brewton, Alabama, DuBose graduated from Huntingdon College with her Bachelor of Arts degree in 1986 and later graduated from the Emory University School of Law in Atlanta with her Juris Doctor in 1989.

[3] DuBose started her legal career as a law clerk to former Judge Peter Beer of the United States District Court for the Eastern District of Louisiana from 1989 to 1990.

In 1994, DuBose was appointed by Governor Jim Folsom Jr. as a deputy attorney general in the Alabama Attorney General's Office from 1994 to 1996 before serving as chief counsel for Alabama U.S.

[3] On the unanimous recommendation of Senators Jeff Sessions and Richard Shelby, DuBose was nominated by President George W. Bush on September 28, 2005 to a seat vacated by Charles Randolph Butler Jr. DuBose was confirmed by the Senate on December 21, 2005 and received her commission on December 27, 2005.