The villain, Fartor wreaks havoc and seeks revenge on his cruel brother by causing a fart epidemic in order to fuel a giant robot called Fartzilla.

Lance Boil builds an infrasound ray gun that causes instant diarrhea, thereby severely hindering any police investigation.

A crazed basketball player creates a plague-like Athlete's Foot epidemic using his new brand of popular running shoes.

A mysterious plague of uncontrollable vomiting has struck the city, even affecting Abby...which may mean the end of her career as a Grossologist.

When the GRS-1 is damaged, Ty and Lab Rat design and build the TYMOBILE, a kicking set of wheels that can crawl, leap, or otherwise get around just like a Feline.

Ty is then goaded into a race by Insectiva and her cadre of giant bugs, which is really just a cover for her deeper, evil plan.

In a plot similar to Fantastic Voyage, Lance Boil has perfected his shrink ray, and invaded Ty's body.

Instectiva, Lance Boil and Sloppy Joe join forces to shut down the Bureau of Grossology by afflicting the members simultaneously with villain-sized doses of horseflies, halitosis and acne.

When Abby defuses a mysterious device Lance Boil planted in the middle of town, she gets bathed in green pus that instantly starts her aging at many times the normal rate.

Ty, Abby, Paige and Naomi are locked in the school by a mad proctologist, Dr. Cornelius Colon.

Abby learns what teamwork is all about when she's kidnapped and imprisoned in a hothouse full of giant, man-eating plants, and her only hope for survival is Insectiva!

Abby and Ty are jazzed to be contestants on the hottest game show on the planet where their gross skills and iron stomachs could make them stars.

It also aired on Jetix on June 2, 2007, and Kix (now Pop Max) from September 15, 2008, in the United Kingdom, and on ABC in Australia in December 2007.

Emily Ashby of Common Sense Media gave the show rate three stars out of five, stating that "such topics offer ample breeding ground for jokes as well," and "nearly as entertaining […] but rest assured that, while they're laughing, they'll be learning about science ... or at least it's yuckier side.