He played a total number of 85 matches for Zagłębie and scored 18 times, including appearances in the Polish Cup and UEFA Europa League qualifying stages.

[11] During his following match, a 2–0 victory over Chievo, he scored his 10th goal across all competitions and in the process became the first player across Europe's major leagues to reach the milestone for the season.

[12] On 30 September, Piątek scored a brace inside three minutes in a 2–1 win over Frosinone to make it 8 goals in six matches, the best start to a season by a debutant since Karl Aage Hansen in the 1949–50 campaign.

[14] On 23 January 2019, AC Milan announced the signing of Piątek on a contract lasting until 30 June 2023,[15] for a reported fee of €35 million.

[16] He was signed as a replacement for Gonzalo Higuaín, who joined Chelsea,[17] and he was assigned the number 19 shirt, previously worn by Leonardo Bonucci.

[19] Three days later against the same opponents also at San Siro, he scored both goals in a 2–0 win in the Coppa Italia quarter-finals, and was given a standing ovation when he made way for Cutrone.

[39] Piątek finished that Serie A season with 14 appearances and 3 goals for Fiorentina, helping the club to qualify for the 2022-23 UEFA Europa Conference League play-off round.

[42] On 12 December 2024, he netted a goal and provided an assist in a Conference League group stage match, which concluded in Başakşehir's 3–1 victory over FC Heidenheim.

[45] Piątek's international debut came on 11 September 2018, starting in a 1–1 friendly draw with the Republic of Ireland in Wrocław and making way for Mateusz Klich after 61 minutes.

[46] Exactly one month later, he made his competitive debut in a UEFA Nations League match against Portugal and scored the opening goal in a 3–2 defeat.

[47] Regarded as an important player for the national team and ready to play alongside Robert Lewandowski and Arkadiusz Milik in an attacking trio, Piątek was forced to miss the postponed UEFA Euro 2020 due to ankle injury in May 2021 that required surgery and months of rehabilitation.

[48] On 10 November 2022, Piątek was included in Poland's 2022 FIFA World Cup squad,[49] making two group stage appearances as a substitute.

[53][54] During his time in Genoa, Piątek played in a 3–5–2 formation as a main striker, usually on the left, most often supported by Christian Kouamé, a pacey forward with excellent dribbling and passing skills.

[56] He is called by fans as "Il Pistolero" (the Gunslinger) due to his habit of Wild West celebration of gun-firing, associated with the 19th century United States.