The Kuise River (杭瀬川, Kuise-gawa) is a river in Japan which has its source on Mount Ikeda in Gifu Prefecture.

It drains into the Makita River, which ultimately flows into the Kiso River.

[1] The river passes through or forms the boundary of Ikeda, Ōgaki, Yōrō, and Wanouchi in Gifu Prefecture.

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