Following the renewal of the Maçka Barracks, "Mekteb-i Fünun-ı İdadîye" started its second education year with a ceremony at the presence of Sultan Abdülmecid I on 10 October 1846.

At that time, four military high schools, including Kuleli, were combined under the name of "Umum Mekteb-i İdadî Şahane" and transferred to the Galatasaray Barracks.

For this reason, “Mekteb-i Fünun-ı İdadîye” and “Deniz İdadîsi” (Naval High School) moved to the Kuleli Barracks in 1872.

Therefore, the students and academic staff of Kuleli moved to the Turkish Military Academy building in Pangaltı, Istanbul.

During World War I, the school temporarily moved to the Prinkipo Greek Orthodox Orphanage in Büyükada Island near Istanbul for some time.

Kuleli Military High School applied the curriculum of the Ministry of National Education for science courses until the 1975–76 academic year.

Afterwards, it began to apply the college system and the education period was increased from three to four years, with the addition of a Prep Class.