The Kure Line (呉線, Kuresen) is a railway line operated by West Japan Railway Company (JR West) within Hiroshima Prefecture in Japan.

The Kure Line is entirely within Hiroshima Prefecture.

[2] The Kaitashi - Kure section was opened as a private line in 1903, and leased to the Sanyo Railway Co. the following year, before being nationalised in 1906.

Work to duplicate the line at Kure commenced in 1940, but was abandoned due to material shortages in 1945.

The entire line was electrified in 1970, and freight services ceased in 1986.