Kuzino (Russian: Кузино) is an urban locality (an urban-type settlement) under the administrative jurisdiction of the town of oblast significance of Veliky Ustyug, Vologda Oblast, Russia, located on the right bank of the Northern Dvina River at the confluence of the Sukhona and the Yug Rivers, opposite to Veliky Ustyug.

In 1930s, it grew up due to the construction of the mechanical works, and the nearby village of Yesiplevo was merged into Kuzino.

In the past, the main industrial enterprise in Kuzino was the mechanical works which went bankrupt and stopped operation in 2000s.

In winter, the rivers freeze, and cars and trucks cross the Northern Dvina over the ice.

An unpaved road connects Kuzino with Luza in Kirov Oblast and continues to Lalsk and further to the Komi Republic.